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FAQs

Does saffron really work for weight-loss? ›

Research suggests that saffron may help reduce appetite and help with weight management, especially if you have obesity. For example, a 2023 study found that taking 60 mg of saffron per day for 12 weeks was significantly more beneficial than a placebo in reducing body mass index (BMI), waist circumference, and weight.

Some common side effects include drowsiness, stomach problems, and nausea or vomiting. Allergic reactions are also possible. Taking large amounts of saffron by mouth is possibly unsafe. High doses of 5 grams or more can cause poisoning.

While berberine is not a magic weight-loss pill, it may help people with a body mass index (BMI) over 30 lose weight. Two studies have shown that taking a supplement for 3 months results in significant weight loss. This may be because berberine helps control insulin and other hormones that regulate your fat cells.

Take a pinch of saffron extract once a day to manage hunger and control your appetite. It is advised to take it on an empty stomach for best results, suggests the expert.

How long do you need to take saffron to start experiencing its benefits? Saffron is water-soluble, so it will absorb into your body quickly. Like most supplements, however, the effects of saffron are cumulative, so you may need to take this spice for a few weeks to notice significant effects.

Saffron may trigger mood swings in people with bipolar disorder. Women who are pregnant or breastfeeding should not use saffron. Interactions. When used as a supplement, saffron may cause problems for people on blood pressure medicine or blood thinners.

Saffron is a natural source of the antioxidant glutathione, which plays a role in helping (2) your body to detox through supporting your liver – your body's main detox organ. In addition, glutathione (3) leads to cell regeneration and a healthy gut.

Saffron is not prohibited for use by Service Members, and should not cause a positive result on a routine military drug test.

For mood enhancement: If you're aiming to tap into saffron's potential mood-enhancing effects, it could be beneficial to take it during the daytime, preferably in the morning. This timing could contribute to uplifting your mood and enhancing emotional wellbeing throughout your day.

Berberine is touted as a "natural" version of semaglutide drugs like Ozempic, but it's not an exact replacement. There are also too few studies that prove berberine can suppress appetite and lead to weight loss.

Why don't doctors recommend berberine? ›

Berberine can interact with prescription medications and increase or decrease levels of these medicines in the blood due to its effects on specific enzymes in the blood. This is especially true of drugs like metformin metabolized by the liver. There may also be an increased risk of bleeding.

Berberine should be avoided by those who are pregnant or breastfeeding, as it may worsen jaundice in infants or result in kernicterus, a condition in which prolonged high bilirubin levels can cause irreversible effects ⁽²⁸⁾.

Taking large amounts of saffron by mouth is POSSIBLY UNSAFE. High doses can cause poisoning, including yellow appearance of the skin, eyes, and mucous membranes; vomiting; dizziness; bloody diarrhea; bleeding from the nose, lips, and eyelids; numbness; and other serious side effects.

Research has shown that taking a saffron extract supplement can aid in weight loss. One 8-week study showed that individuals who took saffron extract had a significant reduction in appetite, waist circumference, and total fat mass. Always speak with a healthcare provider before starting a supplement for weight loss.

Twenty minutes of exposure to the odor of saffron (even though diluted below recognition) had a significant effect on these young women: It decreased cortisol levels and increased estrogen levels.

Having antioxidant properties, saffron can be regarded as an agent to prevent the gastric mucosa damage through enriching the glutathione levels as well as reducing the lipid peroxidation (8).

Saffron water is loaded with antioxidants that help in healing and regenerating brain cells. In fact, several studies suggest that saffron may have antidepressant properties that help in boosting brain strength and has mood-improving effects. It may help reduce symptoms of depression and anxiety in some cases.

Kesar milk, with its natural sedative properties, can play a crucial role in promoting restful sleep. The compounds present in saffron are believed to stimulate serotonin production, a neurotransmitter that regulates mood and sleep.

Saffron is a brightly-colored spice that's high in health-promoting compounds, such as carotenoid antioxidants. Research findings suggest saffron has anti-inflammatory and antioxidant effects and may improve heart health, reduce symptoms of depression and anxiety, improve sleep, and protect eye health.